Clark Gable, Myrna Loy, William Powell. While I suppose it would be possible for those people to make an unwatchable movie, this isn't it.
Gable and Powell play Blackie and Jim, respectively. They are literally boyhood chums. A tragic riverboat fire bonds them for life, but they take divergent paths: Jim becomes a crusading attorney, destined to root out organized crime and corruption, while Blackie adopts the path of a gentleman gangster, with a slightly off-kilter sense of honor about him.
Myrna Loy, lovely as always, is Eleanor, initially Blackie's moll, but won away (literally) overnight by Jim, as she realizes Blackie's essential disreputableness, and is charmed by Jim's honorable intentions and traditional values.
All this—well, you see the title—sets up inevitable conflict driven by a contrived plot. And it's all pretty good stuff, because those three can make anything believable, and make you care about how things are going to turn out.