To be honest, I'm not sure if I've ever made it through the original Blade Runner without nodding off somewhere or other in the middle. All those dark artsy atmospherics kind of put me to sleep.
And similarly with Blade Runner 2049, I'm sorry to say. First try was a dismal failure, as I cut out about twenty minutes in. Second try was better, I'm pretty sure I only missed a few minutes. Or maybe slightly more than a few minutes. Difficult to tell, really. It's very long (only 17 minutes short of three hours).
Ryan Gosling plays "K"; like Harrison Ford's original Deckard, he's a replicant (sorry, spoiler there for the original) who's tasked with hunting down and (if necessary, and it's always necessary) terminating fugitive replicants.
His latest mission uncovers a decades-old box of bones. They're easy to track down because of a replicant serial number, and—guess what—they are Rachael's. And they can tell she died in childbirth. Oh oh.
So K starts looking for the missing kid, which involves him finding (I'm pretty sure you know this already) Deckard. But the Evil Corporate Forces behind it all have their own plans too, involving (for some hazily-specified reasons) heartless and arbitrary violence.
I liked this mainly for Harrison Ford's performance; I think he should have gotten an Oscar for it. And the great Edward James Olmos comes back as Very Old Gaff, too.
Moral, I think: always make sure your girlfriend is routinely backed up to the cloud.