There are probably a lot of better movies available to me, but (never mind the details) I was in no mood to find them among a plethora of options. So I picked this Netflix streamer off their front page.
Emily and Lydia become buddies in school, where brash and combative Lydia defends shy, studious Emily from the insults and bullying from their fellow classmates. But they have a falling out, and Lydia grows up to be a dockworker (and be played by Melissa McCarthy). Emily (Octavia Spencer) has become a scientist, specializing in…
Well, never mind that, because there's a problem: One of those freaky radioactive space storms has unleashed a wave of mutations upon Earth, giving rise to the "Miscreants", super-powered bad guys. And one of them (for no apparent reason) murdered a bunch of people on a Chicago commuter train, including Emily's parents.
OK, so Emily's out for revenge. Her research leads her to develop the power of invisibility. And through a merry mixup, Lydia gets super-strength and invulnerability. And they are off to fight crime.
This is played mostly for laughs. Bobby Cannavale plays "The King", the evil head of the Miscreants gang, and Jason Bateman is one of his underlings, "The Crab". I'm fuzzy about what superpowers the Crab was supposed to have, but he does have crab claws instead of lower arms. And in one of their early battles, it becomes apparent that he and Lydia might have feelings for each other, and his heart is not entirely black.
There are a lot of goofy lines, some of which work. I can't recommend it, but you might like it if you're in the mood.